{"id":47214,"date":"2026-04-06T13:20:39","date_gmt":"2026-04-06T10:20:39","guid":{"rendered":"https:\/\/hyperpower.com.tr\/?p=47214"},"modified":"2026-05-14T11:10:30","modified_gmt":"2026-05-14T08:10:30","slug":"spermidine-ve-otofaji-hucresel-temizlik-neden-bu-kadar-onemli","status":"publish","type":"post","link":"https:\/\/hyperpower.com.tr\/en\/spermidine-ve-otofaji-hucresel-temizlik-neden-bu-kadar-onemli\/","title":{"rendered":"Spermidine ve Otofaji: H\u00fccresel Temizlik Neden Bu Kadar \u00d6nemli?"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"47214\" class=\"elementor elementor-47214\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-14216d2 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"14216d2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e1e5713 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-image\" data-id=\"e1e5713\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1672\" height=\"941\" src=\"https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-30x30.png\" class=\"attachment-2048x2048 size-2048x2048 wp-image-48331 cmsmasters_img cmsmasters-lazyload lazyload\" alt=\"\" data-sizes=\"(max-width: 1672px) 100vw, 1672px\" data-src=\"https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak.png\" data-srcset=\"https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak.png 1672w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-300x169.png 300w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-1024x576.png 1024w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-768x432.png 768w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-1536x864.png 1536w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-533x300.png 533w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-500x281.png 500w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-700x394.png 700w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-30x16.png 30w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-18x10.png 18w\" srcset=\"https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-300x169.png 300w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-1024x576.png 1024w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-768x432.png 768w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-1536x864.png 1536w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-533x300.png 533w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-500x281.png 500w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-700x394.png 700w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-30x16.png 30w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak-18x10.png 18w, https:\/\/hyperpower.com.tr\/wp-content\/uploads\/2026\/04\/spermidine-blog-kapak.png 1672w\" sizes=\"(max-width: 1672px) 100vw, 1672px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-995f266 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"995f266\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b903934 elementor-widget__width-inherit cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"b903934\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Zaman\u0131n etkisi \u00e7o\u011fu zaman y\u00fczeyde ba\u015flar gibi g\u00f6r\u00fcn\u00fcr.<br data-start=\"372\" data-end=\"375\" \/>Oysa as\u0131l de\u011fi\u015fim, h\u00fccre i\u00e7inde daha sessiz ilerler.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55274cbb elementor-widget__width-inherit cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"55274cbb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">H\u00fccreler, normalde d\u00fczenli olarak kendi i\u00e7indeki hasarl\u0131 yap\u0131lar\u0131 temizler ve yeniden kullan\u0131r. <\/span><span style=\"font-weight: 400;\">Ancak bu temizlik s\u00fcreci zamanla daha az verimli hale gelebilir.<\/span><\/p><p><span style=\"font-weight: 400;\">Bu noktada, h\u00fccre i\u00e7inde uzakla\u015ft\u0131r\u0131lmas\u0131 gereken yap\u0131lar\u0131n birikimi artar\u00a0<\/span><span style=\"font-weight: 400;\">ve sistem, fark edilmeden daha \u201cyo\u011fun\u201d \u00e7al\u0131\u015fmaya ba\u015flar.<\/span><\/p><p><span style=\"font-weight: 400;\">Bu s\u00fcrecin merkezinde, h\u00fccrenin kendi i\u00e7ini temizledi\u011fi do\u011fal mekanizma yer al\u0131r: <\/span><b>otofaji<\/b><span style=\"font-weight: 400;\">.\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">Ve son y\u0131llarda bu mekanizmayla birlikte ad\u0131 daha s\u0131k an\u0131lan bir bile\u015fik var: <\/span><span style=\"text-decoration: underline;\"><b><a href=\"https:\/\/www.amazon.com.tr\/dp\/B0GQBPQV9N\" target=\"_blank\" rel=\"noopener\">Spermidine<\/a><\/b><span style=\"font-weight: 400;\">.<\/span><\/span><\/p><h2><strong>Otofaji nedir?<\/strong><\/h2><p><span style=\"font-weight: 400;\">Otofaji, h\u00fccrenin kendi i\u00e7inde yapt\u0131\u011f\u0131 bir temizlik ve geri d\u00f6n\u00fc\u015f\u00fcm s\u00fcrecidir.<\/span><\/p><p><span style=\"font-weight: 400;\">Hasarl\u0131 proteinler, i\u015flevini yitirmi\u015f yap\u0131lar ve zamanla biriken h\u00fccresel \u201cat\u0131klar\u201d bu sistem sayesinde par\u00e7alan\u0131r ve yeniden kullan\u0131l\u0131r.\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">Ayn\u0131 zamanda bir t\u00fcr <\/span><b>kalite kontrol mekanizmas\u0131<\/b><span style=\"font-weight: 400;\"> gibi \u00e7al\u0131\u015f\u0131r:<\/span><span style=\"font-weight: 400;\"><br \/><\/span><span style=\"font-weight: 400;\"> H\u00fccre, neyin kalmas\u0131 neyin gitmesi gerekti\u011fine karar verir.\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">Bu s\u00fcre\u00e7:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">h\u00fccresel dengeyi korumaya yard\u0131mc\u0131 olur<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">sistemin d\u00fczenli \u00e7al\u0131\u015fmas\u0131n\u0131 destekler<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">ya\u015fla birlikte yava\u015flayabilir<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">Otofajinin zamanla yava\u015flamas\u0131, h\u00fccre i\u00e7inde hasarl\u0131 yap\u0131lar\u0131n birikmesiyle ve ya\u015flanma s\u00fcre\u00e7leri ile ili\u015fkilendirilmektedir.\u2074<\/span><\/p><p><b>Ya\u015flanma \u00e7o\u011fu zaman birikimdir.<\/b><b><br \/><\/b><b> Otofaji ise temizlik.<\/b><\/p><h2><strong>Spermidine nedir?<\/strong><\/h2><p><span style=\"font-weight: 400;\">Spermidine, hem v\u00fccutta \u00fcretilen hem de besinlerle al\u0131nabilen do\u011fal bir bile\u015fiktir.\u00b9<\/span><\/p><p><span style=\"font-weight: 400;\">T\u00fcm canl\u0131 organizmalarda bulunur ve h\u00fccre i\u00e7i dengenin korunmas\u0131nda rol oynar.<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u00fccre b\u00fcy\u00fcmesi<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">DNA ve RNA stabilitesi<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Protein \u00fcretimi<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u00fccresel denge<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">gibi bir\u00e7ok temel s\u00fcre\u00e7le ili\u015fkilidir.\u00b9<\/span><\/p><p><span style=\"font-weight: 400;\">Ayn\u0131 zamanda h\u00fccresel koruma, mitokondri fonksiyonlar\u0131 ve stres yan\u0131t\u0131 ile ba\u011flant\u0131l\u0131 mekanizmalarda rol oynad\u0131\u011f\u0131 g\u00f6sterilmi\u015ftir.\u00b9<\/span><\/p><p><strong>Spermidine ve otofaji aras\u0131ndaki ba\u011flant\u0131:<\/strong><\/p><p><span style=\"font-weight: 400;\">Son y\u0131llarda yap\u0131lan \u00e7al\u0131\u015fmalar, Spermidine\u2019in otofaji s\u00fcrecinin \u00f6nemli d\u00fczenleyicilerinden biri olabilece\u011fini g\u00f6stermektedir.<\/span><\/p><p><span style=\"font-weight: 400;\">Ara\u015ft\u0131rmalar, Spermidine\u2019in otofajiyi destekleyen biyolojik yollar \u00fczerinde etkili oldu\u011funu ortaya koymaktad\u0131r.\u00b2<\/span><\/p><p><span style=\"font-weight: 400;\">Bu etki birka\u00e7 farkl\u0131 mekanizma \u00fczerinden ger\u00e7ekle\u015fir:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Otofajiyi bask\u0131layan baz\u0131 enzimlerin aktivitesini s\u0131n\u0131rlayabilir<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u00fccresel enerji sens\u00f6rleri (AMPK \/ mTOR) \u00fczerinden otofaji sinyallerini etkileyebilir<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u00fccresel temizlik s\u00fcre\u00e7lerini y\u00f6neten d\u00fczenleyici sistemlerle ba\u011flant\u0131l\u0131 olabilir<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mitokondri sa\u011fl\u0131\u011f\u0131 ve h\u00fccresel enerji \u00fcretimi ile ili\u015fkili mekanizmalarda rol oynayabilir\u00b2<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">Bu mekanizmalar birlikte de\u011ferlendirildi\u011finde, <a href=\"https:\/\/www.amazon.com.tr\/dp\/B0GQBPQV9N\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Spermidine<\/span><\/a>\u2019in h\u00fccre i\u00e7i temizlik ve denge s\u00fcre\u00e7leriyle g\u00fc\u00e7l\u00fc bir ba\u011flant\u0131s\u0131 oldu\u011fu g\u00f6r\u00fclmektedir.<\/span><\/p><h2><strong>Neden bu kadar konu\u015fuluyor?<\/strong><\/h2><p><span style=\"font-weight: 400;\">Otofaji yaln\u0131zca bir temizlik sistemi de\u011fildir.<\/span><span style=\"font-weight: 400;\"><br \/><\/span><span style=\"font-weight: 400;\"> Ayn\u0131 zamanda h\u00fccrenin stresle ba\u015fa \u00e7\u0131kma ve uyum sa\u011flama mekanizmas\u0131n\u0131n bir par\u00e7as\u0131d\u0131r.\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">\u00d6zellikle besin k\u0131s\u0131t\u0131 gibi durumlarda, h\u00fccreye enerji \u00fcretimi i\u00e7in gerekli yap\u0131 ta\u015flar\u0131n\u0131 sa\u011flayabilir.\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">Bu nedenle otofaji:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">beyin fonksiyonlar\u0131<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">ba\u011f\u0131\u015f\u0131kl\u0131k sistemi<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">metabolik denge<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">kalp sa\u011fl\u0131\u011f\u0131<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">gibi bir\u00e7ok sistemle ba\u011flant\u0131l\u0131 olarak ele al\u0131nmaktad\u0131r.\u00b2\u2074<\/span><\/p><p><span style=\"font-weight: 400;\">Ayr\u0131ca baz\u0131 \u00e7al\u0131\u015fmalar, Spermidine\u2019in a\u00e7l\u0131k ve kalori k\u0131s\u0131tlamas\u0131 s\u0131ras\u0131nda ortaya \u00e7\u0131kan otofaji yan\u0131tlar\u0131nda rol oynayabilece\u011fini \u00f6ne s\u00fcrmektedir.\u00b2<\/span><\/p><h2><b>Ya\u015fla birlikte ne de\u011fi\u015fiyor?<\/b><\/h2><p><span style=\"font-weight: 400;\">Ara\u015ft\u0131rmalar, spermidine seviyelerinin ya\u015fla birlikte azald\u0131\u011f\u0131n\u0131 g\u00f6stermektedir.\u00b9<\/span><\/p><p><span style=\"font-weight: 400;\">Bu azalma:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">otofaji s\u00fcre\u00e7lerinin yava\u015flamas\u0131yla<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">h\u00fccre i\u00e7inde hasarl\u0131 yap\u0131lar\u0131n birikmesiyle<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">ili\u015fkili olabilir. <\/span><span style=\"font-weight: 400;\">\u0130lgin\u00e7 bir g\u00f6zlem ise \u015fu: <\/span><span style=\"font-weight: 400;\">Daha y\u00fcksek Spermidine al\u0131m\u0131n\u0131n, baz\u0131 \u00e7al\u0131\u015fmalarda daha d\u00fc\u015f\u00fck genel mortalite ile ili\u015fkili oldu\u011fu g\u00f6sterilmi\u015ftir.\u00b3<\/span><\/p><h2><b>Beslenme ve ya\u015fam tarz\u0131 ba\u011flant\u0131s\u0131<\/b><\/h2><p><span style=\"text-decoration: underline;\"><a style=\"font-style: normal; font-weight: 300; letter-spacing: 0px; word-spacing: 0px;\" href=\"https:\/\/www.amazon.com.tr\/dp\/B0GQBPQV9N\" target=\"_blank\" rel=\"noopener\">Spermidine<\/a><\/span><span style=\"font-weight: 400;\">\u00a0sadece v\u00fccutta \u00fcretilmez.<\/span><span style=\"font-weight: 400;\"><br \/><\/span><span style=\"font-weight: 400;\"> Ayn\u0131 zamanda beslenme ve ba\u011f\u0131rsak mikrobiyotas\u0131 ile de ili\u015fkilidir.\u00b9<\/span><\/p><p><span style=\"font-weight: 400;\">Spermidine a\u00e7\u0131s\u0131ndan zengin baz\u0131 besinler:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">bu\u011fday \u00f6z\u00fc<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">brokoli<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">karnabahar<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">fermente g\u0131dalar<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">Bu nedenle g\u00fcnl\u00fck al\u0131\u015fkanl\u0131klar, h\u00fccresel d\u00fczeyde d\u00fc\u015f\u00fcnd\u00fc\u011f\u00fcm\u00fczden daha fazla rol oynayabilir.<\/span><\/p><h2><b>Bilim ne s\u00f6yl\u00fcyor?<\/b><\/h2><p><span style=\"font-weight: 400;\">Bug\u00fcne kadar yap\u0131lan \u00e7al\u0131\u015fmalar,\u00a0<\/span><a href=\"https:\/\/hyperpower.com.tr\/en\/product\/spermidine\/\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Spermidine<\/span><\/a><span style=\"font-weight: 400;\">\u2019in otofaji ile ili\u015fkili s\u00fcre\u00e7lerde rol oynayabilece\u011fini ve bu mekanizmalar\u0131n sa\u011fl\u0131kl\u0131 ya\u015flanma ile ba\u011flant\u0131l\u0131 olabilece\u011fini g\u00f6stermektedir.\u00b9\u00b2\u00b3<\/span><\/p><p><span style=\"font-weight: 400;\">Ancak \u00f6nemli bir nokta var:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u0130nsanlarda ideal seviyeler hen\u00fcz net de\u011fildir.<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uzun vadeli etkiler h\u00e2l\u00e2 ara\u015ft\u0131r\u0131lmaktad\u0131r.<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Etkiler ba\u011flama ve ko\u015fullara g\u00f6re de\u011fi\u015febilir.<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">V\u00fccut bu sistemleri zaten biliyor.\u00a0 <\/span><span style=\"font-weight: 400;\">Biz sadece zamanla yava\u015flayan s\u00fcre\u00e7leri yeniden anlamaya \u00e7al\u0131\u015f\u0131yoruz. <\/span><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.amazon.com.tr\/dp\/B0GQBPQV9N\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Spermidine<\/span><\/a> ve otofaji, bu b\u00fcy\u00fck resmin \u00f6nemli par\u00e7alar\u0131ndan biri. <\/span><span style=\"font-weight: 400;\">Ama belki de en temel olan\u0131: <\/span><b>Temizlik.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d70ab6e cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"d70ab6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><strong>Kaynak\u00e7a<\/strong><\/h2><ul><li>Madeo, F., et al. (2018).<br data-start=\"150\" data-end=\"153\" \/><em data-start=\"156\" data-end=\"191\">Spermidine in health and disease.<\/em> Science.<\/li><li>Eisenberg, T., et al. (2009).<br data-start=\"234\" data-end=\"237\" \/><em data-start=\"240\" data-end=\"298\">Induction of autophagy by spermidine promotes longevity.<\/em> Nature Cell Biology.<\/li><li>\u00a0Mizushima, N., &amp; Komatsu, M. (2011).<br data-start=\"360\" data-end=\"363\" \/><em data-start=\"366\" data-end=\"411\">Autophagy: renovation of cells and tissues.<\/em> Cell.<\/li><li>Levine, B., &amp; Kroemer, G. (2008).<br data-start=\"455\" data-end=\"458\" \/><em data-start=\"461\" data-end=\"504\">Autophagy in the pathogenesis of disease.<\/em> Cell.<\/li><li>Rubinsztein, D. C., et al. (2011).<br data-start=\"549\" data-end=\"552\" \/><em data-start=\"555\" data-end=\"577\">Autophagy and aging.<\/em> Cell.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Zaman\u0131n etkisi \u00e7o\u011fu zaman y\u00fczeyde ba\u015flar gibi g\u00f6r\u00fcn\u00fcr. Oysa as\u0131l de\u011fi\u015fim, h\u00fccre i\u00e7inde daha sessiz ilerler.<\/p>","protected":false},"author":2,"featured_media":48331,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[120,121,119,118],"class_list":["post-47214","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-hucre-sagligi","tag-hucre-temizligi","tag-otofaji","tag-spermidine"],"acf":[],"_links":{"self":[{"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/posts\/47214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/comments?post=47214"}],"version-history":[{"count":32,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/posts\/47214\/revisions"}],"predecessor-version":[{"id":48356,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/posts\/47214\/revisions\/48356"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/media\/48331"}],"wp:attachment":[{"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/media?parent=47214"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/categories?post=47214"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hyperpower.com.tr\/en\/wp-json\/wp\/v2\/tags?post=47214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}